Our research programme is divided into five areas of focus: brain tumours in children and teenagers; high grade brain tumours; low grade brain tumours; research across brain tumour types; and research at Samantha Dickson Brain Tumour Trust Centres of Excellence.
Research into brain tumours in children and teenagers
University of Cambridge (Professor V Peter Collins) (2010 – 2013), Molecular-genetic and epigenetic analysis of pilocytic & pilomyxoid astrocytomas and ependymomas
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University of Cambridge (Dr Howard Ring) (2008 – 2011), Rates of psychiatric illness in long-term survivors of early childhood brain tumours
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Institute of Cancer Research, Royal Marsden NHS Foundation Trust (Dr Nada Al-Saffar) (2009 – 2012), Establishing non-invasive biomarkers of the efficacy of novel phophoinositide 3-kinase inhibitors in paediatric high-grade glioma by magnetic resonance spectroscopy
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Institute of Cancer Research, Royal Marsden NHS Foundation Trust (Dr Louis Chesler) (2010 – 2013), Systematic analysis of the role of MYCN in the formation and progression of high-grade, anaplastic medulloblastoma
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Institute of Cancer Research, Royal Marsden NHS Foundation Trust (Dr Chris Jones) (2010 – 2012), Systematic characterisation and functional assessment of amplified genes in paediatric glioblastoma
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University of Nottingham (Professor Richard Grundy) (2011 – 2014), The role of histone deacetylase inhibition in malignant childhood ependymoma - Jointly funded with the Joseph Foote Charitable Trust
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University of Nottingham (Professor Richard Grundy) (2008 – 2012), Genome-wide molecular characterisation of supratentorial PNET (sPNET) – II
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Newcastle University (Professor Steven Clifford) (2007 – 2011), The molecular basis of childhood medulloblastoma: from genomics to improved therapies
Newcastle University (Professor Steven Clifford) (2008 – 2012), A feasibility study of real-time biological characterisation of medulloblastoma
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Newcastle University (Professor Steven Clifford) (2011 – 2013), Biomarker discovery for improved disease risk assessment and therapy of childhood medulloblastoma
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Newcastle University (Professor Steven Clifford) (2010 – 2012), Central support for CCLG CNS Tumour clinical trials pathology review and biological studies: funding of a Biomedical Scientist – Jointly funded with Cancer Research UK
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Royal Victoria Infirmary, Newcastle (Dr Simon Bailey) (2010 – 2012) – A phase II multi-centre study of the concomitant and prolonged adjuvant temozolomide with radiotherapy in diffuse pontine gliomas - Jointly funded with Cancer Research UK
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Research into high-grade tumours
University of Cambridge (Dr Colin Watts) (2011 – 2013), An Evaluation of the tolerability and feasibility of combining 5-Amino-Levulinic Acid (5-ALA) with Carmustine Wafers (Gliadel®) in the surgical management of primary glioblastoma – Jointly funded with Cancer Research UK
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University of Wolverhampton (Dr Weiguang Wang) (2008 – 2011), Targeting the Nuclear Factor kappaB (NF-kB) pathway to improve chemotherapy of glioblastoma multiforme
Institute of Neurology, London (Professor Sebastian Brandner) (2008 – 2012), Analysis of LOH 1p/19q and MGMT methylation in patients with malignant gliomas
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Research into low-grade tumours
University of Nottingham (Dr Paul Scotting) (2006 – 2011), Reassessing the origins of cranial germ cell tumours
Research across brain tumour types and age groups
University College London (Dr Susan Short) (2010 – 2012), Clinical Trials Project Officer
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North Bristol NHS Trust (Dr Ingram Wright) (2008 – 2011), Development and evaluation of a neuropsychological follow-up service for survivors of childhood brain tumours
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Clinical and Research Training
University of Edinburgh (Dr Robin Grant) (2009 – 2013), Clinical fellowship in neurological neuro-oncology
Research Centres of Excellence
The Samantha Dickson Brain Cancer Unit, at University College London’s (UCL) Cancer Institute is our first dedicated Research Centre of Excellence. The Centre, which is costing £1,667,511 over five years, is led by Professor Paolo Salomoni and Dr Steven Pollard, both talented researchers with considerable experience in brain tumour research.
